Lonestar

Food Freshness and Flavour Monitoring Food Freshness and Flavour MonitoringLonestar is an easy to use and powerful analyzer for food production and food safety compliance.  The instrument can monitor freshness, flavours, taints or contamination in food and beverages.  It detects aromas, essences and odour chemicals with high accuracy and sensitivity.  Process monitoring with Lonestar can complement a HACCP or ISO 22000 approach to ensuring food safety and quality.
FAIMS Analysis for the identification and monitoring of disease FAIMS Analysis for the identification and monitoring of diseaseThe detection of certain gas phase bio-markers from human biological output is increasingly being used to identify particular illnesses. Using Owlstone’s proprietary FAIMS technology, Lonestar offers a fast and sensitive way to analyse complex biological samples.
Real-time measurement of diacetyl in beer Real-time measurement of diacetyl in beerThe flavor of beer is strongly influenced by the presence of diacetyl and 2,3-pentanedione. Owlstone's Lonestar analyzer can detect and measure levels of these two vicinal diketones (VDKs) in minutes, right on the brewery floor. Offering detection down to 30ppb (parts per billion) and the ability to measure total diketones or free diacetyl, the instrument is ideal for early fermentation monitoring and finished product quality assurance.
Real Time Identification and Monitoring of Trace Contamination Real Time Identification and Monitoring of Trace ContaminationLonestar is an easy to use and powerful analyzer for accurate, real time identification and monitoring of trace contamination. Foods that contain muscle tissue (meat, poultry and fish) can form biological amines through enzymatic and bacterial actions of proteins and amino acids. For example, trimethylamine (TMA) is formed by a stepwise degradation of choline to betaine and then to TMA.
Detection of Bowel Cancer (Colorectal Cancer) Detection of Bowel Cancer (Colorectal Cancer)A study by Arasaradnam et al. has found that FAIMS can be used to differentiate between patients with colorectal cancer and healthy controls, with a sensitivity of 88%, by rapid, non-invasive analysis of volatile organic compounds (VOCs) in urine. Detection of colorectal cancer’s ‘bio-odorant fingerprint’ with FAIMS from patient urine samples represents a major step forward in simple, non-invasive diagnosis.
Differentiating Coeliac Disease From IBS Using Lonestar Differentiating Coeliac Disease From IBS Using LonestarCoeliac disease is an autoimmune condition, in which the immune system mistakenly identifies the gluten found in wheat, rye or barley as a threat. The immune response that is triggered in this way damages the small intestine, reducing the body's ability to absorb nutrients from food. Once identified, the effects of Coeliac disease can be mitigated or even entirely eliminated by adopting a gluten-free diet.
Lung Cancer Diagnosis using Breath Analysis Lung Cancer Diagnosis using Breath AnalysisThe LuCID (Lung Cancer Indicator Detection) project is funded by an SBRI Healthcare development contract, Owlstone is conducting research into the diagnosis of lung cancer by measuring volatile organic compounds (VOCs) in patients' exhaled breath. The goal of LuCID is to save 10,000 lives and save the NHS £245M by 2020 by increasing the rate of detection of stage I lung cancer from the current level of 14.5% to 25% of patients.
Amine Detection with Lonestar Amine Detection with LonestarA variety of amines may be found in oil and gas, both as constituents and as by-products of processes to remove H2S and/or CO2. Lonestar can detect the presence of amines in both crude oil and water backgrounds, allowing in-situ monitoring of concentrations throughout the treatment process. TOPGUARD is a trademark of Baker Hughes Incorporated.
Diagnosing Asthma By Exhaled Breath Analysis Diagnosing Asthma By Exhaled Breath AnalysisAsthma comprises several different inflammatory disease processes in the lung that result in dyspnea, wheezing and loss of quality of life. An estimated 235 million people worldwide are affected.  Treatment currently consist of a trial and error approach in an attempt to match the right patient to the right drug .
Diagnosing Tuberculosis Using Exhaled Breath Analysis Diagnosing Tuberculosis Using Exhaled Breath AnalysisTuberculosis (TB) is currently (2016) responsible for more deaths worldwide than any other infectious agent apart from HIV/AIDS. There are around 8.6 million new cases, and 1.3 million deaths from TB every year. Diagnosis is still mostly performed by trained technicians examining sputum samples under a microscope (WHO tuberculosis factsheet).
Non-invasive identification and monitoring of inflammatory bowel disease (IBD) Non-invasive identification and monitoring of inflammatory bowel disease (IBD)In a joint project with Warwick University and University Hospital Coventry and Warwick, utilizing funding from the Technology Strategy Board (TSB), we are seeking a means to diagnose inflammatory bowel disease (IBD) using Lonestar. Project Aims
Diagnosing Bile Acid Diarrhoea Diagnosing Bile Acid DiarrhoeaChronic diarrhoea is estimated to affect up to 5% of the population. Bile acid diarrhoea (BAD) is a common form of chronic diarrhoea caused by inadequate reabsorption of bile acid produced as part of the fat digestion process. Reabsorption  can be  perturbed  through  disease,  surgical  removal  of  a  length  of  bowel  or through  defects  in certain  regulatory  proteins. Diagnosis currently requires patients to swallow a capsule of radioactive selenium-75 tagged to homochlorotauric acid.
Analyzing Eagle Ford Crude with Lonestar Analyzing Eagle Ford Crude with LonestarThe Eagle Ford Shale Play in Southern Texas is currently (October 2013) the second most productive oil field in the United States, producing some 1.07 million barrels per day . However, after extraction, hazardous levels of hydrogen sulfide may be present in the crude. H2S can be contained or removed with triazine-based scavengers, but leftover scavengers and the reaction byproducts can themselves cause corrosion and fouling downstream. Using the Lonestar portable analyzer, excess scavenger content in crude after treatment can be identified and quantified. For more details, see the Analysis of H2S Scavengers page.
Analysis of Organic Chlorides in Crude Oil Analysis of Organic Chlorides in Crude OilOrganic chloride contamination in crude oil can cause hydrochloric acid to be formed during hydrotreating. The hydrochloric acid then corrodes equipment through accumulation, and can be particularly damaging in crude tower overhead systems. For this reason, organic chloride levels should ideally be kept below 1ppm.
Carbonyl Sulfide in Propane Carbonyl Sulfide in PropaneCarbonyl sulfide is a contaminant in propane that can form corrosive hydrogen sulfide when it undergoes hydrolysis. This process has been implicated in corrosion and compliance-testing failures in the LPG industry. Using Lonestar, the presence of carbonyl sulfide in propane can be quickly identified.
Detecting Acetic Acid in Crude Oil Detecting Acetic Acid in Crude OilAcetic acid is used to prevent the formation and precipitation of naphthenate salts during crude oil separation and desalting. However, excess acetic acid can lead to high corrosion rates (~100mils/year compared to a normal rate of around 5mils/year), and can generate a high chemical oxygen demand in waste water treatment plants. There is therefore a need for rapid, on-site measurement of acetic acid levels.
Prediction of Gastrointestinal Toxicity during Pelvic Radiation Therapy Prediction of Gastrointestinal Toxicity during Pelvic Radiation TherapyThe detection of certain gas phase bio-markers from human biological output is increasingly being used to identify particular illnesses. Using Owlstone’s proprietary FAIMS technology, Lonestar offers a fast and sensitive way to analyse complex biological samples.
Book Conservation Using Lonestar Portable Analyzer Book Conservation Using Lonestar Portable AnalyzerAs stored books age they generate and release volatile organic compounds (VOCs). It has been shown that the release of certain emitted VOCs (such as furfural) is correlated to the extent of paper degradation in a book. The Lonestar portable gas analyzer can be used to detect VOCs associated with paper degradation and aid in the conservation of antique books, manuscripts and other paper based artifacts.
Detecting sulfites and SO2 using Lonestar Detecting sulfites and SO2 using LonestarThe Lonestar portable analyzer is able to detect whether Traditional Chinese Medicines (TCM), herbal remedies and alternative medicine products contain sulphites by detecting the presence of trace amounts of sulfur dioxide (SO2). Sulfite sensitivity affects many people making the presence of sulfites in herbal medicines a common concern for consumers.
Detecting potato rot with Lonestar Detecting potato rot with LonestarMaintaining the quality and health of stored potatoes is vital for growers, processors and consumers but each year there are consistent and substantial losses due to storage diseases. The Lonestar portable freshness monitor can detect volatile chemical signatures associated with bacterial diseases such as blackleg and potato soft-rot in real time. This allows the early detection and isolation of rotten potato stock, helping to prevent further losses.
Detection of Metaldehyde in Water Using Lonestar Detection of Metaldehyde in Water Using LonestarLonestar offers rapid detection and monitoring of metaldehyde at concentrations low enough to meet the European and UK regulations for pesticides in drinking water. Lonestar can be operated on site by non-specialist personnel to monitor water for metaldehyde in only a matter of minutes.
Quality control of spices using Lonestar Quality control of spices using LonestarThe Lonestar gas analyzer can be used to rapidly identify and measure the volatile essential oil content of spices such as cinnamon, cumin, ginger and cloves. With sampling taking only 10s of seconds, Lonestar offers a fast alternative to time consuming distillation methods for quality control.
Dimethyl sulfate gas detection using Lonestar Dimethyl sulfate gas detection using LonestarLonestar can be used as a dimethyl sulfate (DMSO4) gas monitor for ambient air. DMSO4 is a highly toxic but commonly used industrial methylating agent. Lonestar can continuously sample air and raise the alarm if the concentration of DMSO4 rises above a specified threshold level.
Rapid Screening of Plastic Bottles for dibasic esters Rapid Screening of Plastic Bottles for dibasic estersThe Lonestar portable analyzer allows rapid detection of bottle rinse cleaning solvent DBE-3 (dibasic esters) and DMS (dimethyl sebacate) in PET (polyethylene terephthalate) beverage bottles and food containers at concentrations below 50 ppb, aiding compliance with FDA food contact notifications.
Validating Clean in Place Processes Using Lonestar Validating Clean in Place Processes Using LonestarFast validation of Clean in Place (CIP) cycles by monitoring the composition of rinse water is vital to ensure adequate tank cleaning and for the optimisation of production processes in the food, beverage and pharmaceutical sectors. Lonestar delivers rapid, sensitive and accurate monitoring of rinse water helping to reduce water and cleaning product consumption.
2,4 dichlorophenol in milk detection with Lonestar 2,4 dichlorophenol in milk detection with LonestarLonestar is an easy to use and powerful analyzer for accurate, real time identification and monitoring of trace flavor contamination in milk including 2,4-dichlorophenol (DCP), 2,4-dibromophenol (DBP), biogenic amines such as triethylamine (TEA), milk adulterant benzoic acid and the milk age marker lactic acid.
Tribromoanisole Detection with Lonestar Tribromoanisole Detection with LonestarLonestar is able to rapidly detect tribromoanisole (TBA) at concentrations as low as 10 ppt. TBA has been identified as a common contaminant in the pharmaceutical, food and wine industries. It has been cited by the FDA as a cause for concern and has been the reason for a number of product recalls.
Pharmaceutical waste water analysis Pharmaceutical waste water analysisWaste water treatment by bacteriological biodegradation is used to treat waste water streams (e.g. pharmaceutical, environmental bioremediation). Excesses of some solvents in the waste water can poison the microbes - reducing their efficiency. Consequently there is value in being able to quickly measure concentrations of these critical solvents so they can be pretreated/diluted to protect the bacteria.
Screening and age monitoring of edible oils Screening and age monitoring of edible oilsWithin the edible oils industry, Lonestar can offer at-line screening and monitoring of raw material contamination; flavor thresholds; preservative levels; fatty acid methyl esters; and residues from cleaning-in-place.
Oil Assay - Methanol Analysis Oil Assay - Methanol AnalysisMethanol in crude oil impacts water treatment systems in refineries because bacteria involved in cleansing the water preferentially break down methanol, leaving hydrocarbons and toxins untreated. Methanol is miscible in water, so is present in the desalter effluent. Refineries often choose to cut crude runs rather than risk a "bug kill" - a large upset that would require major remediation and could cause violation of environmental legislation, permit excursions or future penalties.
Propofol (2,6-diisopropylphenol) Anaesthetic Detection Propofol (2,6-diisopropylphenol) Anaesthetic DetectionPropofol (2,6-diisopropylphenol, a.k.a. Diprivan) is used as an intravenous general anaesthetic. Existing measurement techniques for IV anaesthetics require offline blood samples, making them unsuitable for monitoring anaesthetic depth and for ensuring patient safety. The Owlstone Lonestar Analyzer is able to detect propofol at sub part per billion concentrations in under 10 seconds. In addition, Lonestar is highly portable and can be operated by non-specialists.
Analysis of Scavengers for Sulfide (H2S) Removal from Crude Oil Analysis of Scavengers for Sulfide (H2S) Removal from Crude OilTriazine compounds are commonly used as scavenger chemicals to remove hydrogen sulfide (H2S) from crude oil, in a process sometimes called "stripping".  These triazine-based additives are often present in excess of the levels required to remove the H2S. The excess triazine, together with the by-products of the scavenging reaction with H2S, may cause corrosion and fouling in downstream equipment. Consequently, there is value in petroleum processors being able to quickly measure excess concentration of scavenger before custody transfer.
Rapid Detection of Geosmin, Fuels and Pesticides in Water Supplies Rapid Detection of Geosmin, Fuels and Pesticides in Water SuppliesMonitor drinking water supplies to detect geosmin, fuel (diesel/gasoline/petrol), metaldehyde and other chemical contaminants. Using Lonestar analyzers, utilities can mitigate contamination incidents and avoid taste/odor complaints. Combat tightening regulations and terrorist threats, reduce the costs of supplying consumers, industry and food manufacturing. See the instrument work in the video.
Benzene Analysis and Detection Benzene Analysis and DetectionLonestar is a portable gas monitor capable of rapid and accurate benzene analysis. Lonestar can monitor and detect benzene even in a complex background matrix that includes toluene, xylene and other gases (volatile organic compounds, VOCs) that commonly cause false alarms in other detectors.
Rapid Analysis of 4 Methyl Imidazole (4-MEI) Rapid Analysis of 4 Methyl Imidazole (4-MEI)The Lonestar Analyzer can detect and quantify 4-Methyl-Imidazole (4-MEI, also sometimes called 4-MI) within 15 minutes, in a range of backgrounds, including caramels and soy sauce. Deploy Lonestar to ensure compliance with Proposition 65 and improve plant throughput and productivity.
Detection of Melamine in Milk Detection of Melamine in MilkMelamine is an organic base that is widely used in plastics, adhesives, dishware and whiteboards. However, in China, it is sometimes illegally added into milk powder, liquid milk and other dairy products to increase the apparent protein content. A WHO white paper published in the wake of the 2008 Chinese milk scandal concluded that ingesting melamine can lead to the formation of kidney stones and other kidney damage. In 2012, The UN food standards body, Codex Alimentarius Commission, lowered the maximum limit for dairy products to 0.15mg/kg.
Residual Solvent Monitoring with Lonestar Residual Solvent Monitoring with LonestarLonestar is a powerful, easy to use analyzer for accurate, real time identification and monitoring of Class 1, 2 and 3 residual solvents as outlined by The International Conference on Harmonisation (ICH) guidance documents and the United States Pharmacopeia (USP).